How Are the Gene Interaction Maps That Are Made by Analysis

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The Answer is Genetic interaction maps from synthetic genetic arrays define associations as pairs of genes that show synthetic interactions;thus any two genes whose loss of function mutants are lethal or sick in combination but not individually,are connected by a line on the diagram.In protein interaction maps,nodes representing proteins are connected if they are found to physically interact either in yeast two-hybrid screens or in affinity capture experiments.Thus,the protein interaction maps indicate physical interactions between proteins,which like means that the proteins are part of the same pathway or complex.This contrasts with the genetic interaction maps,in which interacting proteins are often considered to be in parallel pathways and do not necessarily interact physically.

How Are the Gene Interaction Maps That Are Made by Analysis

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