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The Following Questions Refer to the Excerpt Below

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The following questions refer to the excerpt below.
"In the middle of the fifteenth century,Europe,Africa,and the Americas came together,creating-among other things-a new economy.At the center of that economy was the plantation,an enterprise dedicated to the production of exotic commodities-the most prominent being sugar-for a distant market.The sugar plantation,which first developed in the Mediterranean,was an enormously complex unit of production requiring the mobilization of vast amounts of capital,the development of new technologies (agricultural,industrial,and maritime) ,the invention of management techniques,and-because sugar production was extraordinarily labor intensive-the employment of huge numbers of workers."
Historian Ira Berlin,"The Discovery of the Americas and the Transatlantic Slave Trade"
-Which of the following historical events did not precede the events described by historian Ira Berlin?

Explain the efficiency of fetal hemoglobin in oxygen transportation.
Analyze the shift in the oxygen-hemoglobin dissociation curve during exercise.
Describe the mechanisms of oxygen and carbon dioxide transport in blood.
Understand the biochemical processes involved in gas exchange in the lungs.

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