Convert the following addition problem into two's complement notation (using four bits per value), perform the addition, convert the answer back into base ten notation, and explain the results. 
Definitions:
Lung Cancer
A type of cancer that originates in the lungs, primarily associated with smoking tobacco, but also related to various environmental factors.
Pharmacological Approaches
Methods involving the use of drugs and medications to treat or manage medical conditions.
Teenage Smokers
Individuals typically aged 13 to 19 who are engaged in the act of smoking tobacco products.
Elderly Smokers
Older adults, typically regarded as those aged 65 and over, who engage in the habit of smoking tobacco.
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