Why Are Leading and Lagging Strand Primers Removed Rather Than

question 24

Multiple Choice

Why are leading and lagging strand primers removed rather than joined with Okazaki fragments?

• A) They lack the 3' OH that would permit them to be covalently linked to the Okazaki fragments.
• B) The primers do not hydrogen bond to the template strand correctly.
• C) They contain nucleotides with 2'OH groups, and are targeted for excision by DNA Polymerase.
• D) They have to be removed for leading and lagging strand synthesis to begin.
• E) Primers are too short to efficiently bind to Okazaki fragments.

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Definitions:

Correlational Study

A research method used to determine the relationship between two variables, without inferring a cause-and-effect relationship.

Directionality Problem

An issue in correlational studies where it is unclear which variable causes changes in the other.

Third Variable Problem

A challenge in research where a correlation between two variables may be explained by the presence of a third variable that influences both.

Random Error

Variability in measurement or data that arises from unpredictable fluctuations during the data collection process.