In the Biosynthetic Pathway for Conversion from Homoserine to Methionine

question 6

Multiple Choice

In the biosynthetic pathway for conversion from homoserine to methionine, you identify a Neurospora crassa double mutant Met1/Met2. This mutant will grow only if which supplement(s) are added to the minimal media?
$\begin{array} { l } \text { Growth Medium }\\\hline \begin{array} { l } \text { Mutant }\\ \text {strain }\\\end{array}&\begin{array} { l } \text { Minimal}\\ \text { medium}\\\end{array}&\begin{array} { l } \text { Minimal+}\\ \text {cysteine }\\\end{array}&\begin{array} { l } \text { Minimal+}\\ \text {cystathionine }\\\end{array}&\begin{array} { l } \text {Minimal+ }\\ \text {homocysteine }\\\end{array}&\begin{array} { l } \text { Minimal+}\\ \text { methionine}\\\end{array}&\begin{array} { l } \text { Compound}\\ \text { accumulating}\\ \text { in mutant}\\\end{array}\\\hline\begin{array} { l } \text { Control}\\ \text {prototroph }\\\end{array}&+&+&+&+&+& \text {None }\\\text { Met } 1&-&-&-&-&+&\text { Homocysteine }\\\text { Met } 2&-&-&-&+&+&\text { Cystathionine }\\\text { Met } 3&-&-&+&+&+&\text { Cysteine }\\\text { Met } 4&-&+&+&+&+&\text { Homoserine }\\\end{array}$

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