Patients Who Have a Poor Metabolism Phenotype Will Have

question 5

Multiple Choice

Patients who have a poor metabolism phenotype will have:

• A)Slowed metabolism of a prodrug into an active drug, leading to accumulation of prodrug
• B)Accumulation of inactive metabolites of drugs
• C)A need for increased dosages of medications
• D)Increased elimination of an active drug

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Definitions:

Dummy Variable

A variable used in regression analysis that assumes the value 0 or 1 to indicate the absence or presence of some categorical effect.

Independent Variable

A variable that is manipulated to determine its effect on a dependent variable within an experimental study.

3-ethyl-3-methylhexane

A branched alkane with the formula C8H18, having an ethyl and a methyl group on the third carbon of the hexane chain.

Ethyl

A univalent radical, C2H5, derived from ethane and forming many compounds, used in chemical synthesis.