Why Is Acidic Amide Hydrolysis Irreversible

question 4

Multiple Choice

Why is acidic amide hydrolysis irreversible?

• A)The amine leaving group is protonated, forming an ammonium ion.
• B)The amide carbonyl is protonated.
• C)The amine leaving group is deprotonated, forming an amide ion.
• D)The carboxylic acid formed in the reaction is deprotonated.
• E)The amine formed in the reaction is deprotonated.

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