Use the Following Information to Answer the Next Few Questions

question 20

Multiple Choice

Use the following information to answer the next few questions.
Pharmacogenetics is an increasingly important discipline that uses genetic information to tailor the prescription of drug treatments to individuals. In the case of chemotherapy for breast cancer, for example, different patients need and/or respond to different treatments.
-Patients whose tumors are HER-2 positive respond to herceptin whereas other patients do not. Patients whose tumors have estrogen receptors will be best served if

• A) their estrogen receptors are blocked by using RNAi.
• B) their estrogen release is activated and/or elevated.
• C) the estrogen receptors are blocked by other molecules that can use the same receptors.
• D) they are given herceptin as well as estrogen.
• E) they are given a complete hysterectomy.

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Definitions:

Effective Interest Rate

This is the actual return on an investment, taking into account the effect of compounding interest as opposed to the nominal rate.

Bond Issue Costs

Expenses associated with the issuance of bonds, including legal, accounting, underwriting fees, and other costs that are often amortized over the life of the bond.

IFRS

International Financial Reporting Standards; a set of accounting standards developed by the International Accounting Standards Board (IASB) aiming for global consistency in financial reporting.

Maturity Value

The amount of money an investment will earn and pay out at the end of its life, including the initial principal and all accumulated interest.