The Following Questions Refer to the Following Paragraph

question 11

Multiple Choice

The following questions refer to the following paragraph.
HIV's genome of RNA includes the code for reverse transcriptase (RT) , an enzyme that acts early in infection to synthesize a DNA genome off of an RNA template. The HIV genome also codes for protease (PR) , an enzyme that acts later in infection by cutting long viral polyproteins into smaller, functional proteins. Both RT and PR represent potential targets for antiretroviral drugs. Drugs called nucleoside analogs (NA) act against RT, whereas drugs called protease inhibitors (PI) act against PR.
-Within the body of an HIV-infected individual who is being treated with a single NA, and whose HIV particles are currently vulnerable to this NA, which of these situations can increase the virus' relative fitness?
1) mutations resulting in RTs with decreased rates of nucleotide mismatch
2) mutations resulting in RTs with increased rates of nucleotide mismatch
3) mutations resulting in RTs that have proofreading capability

• A) 1 only
• B) 2 only
• C) 3 only
• D) 1 and 3
• E) 2 and 3

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Definitions:

PR Pioneers

Individuals who have significantly contributed to the development and advancement of the public relations profession through innovative practices and theories.

George Creel

was a journalist and politician known for heading the Committee on Public Information during World War I, which was an early example of government propaganda.

Amos Kendall

An American journalist, lawyer, and politician, best known for his role as a close advisor to Presidents Andrew Jackson and Martin Van Buren and for his contributions to the field of communication.

Nonprofit Organizations

Entities that operate for purposes other than making a profit, often focusing on social, educational, charitable, or cultural goals.