The Lambda Genome Is Replicated by a Rolling Circle Mechanism

question 36

Multiple Choice

The lambda genome is replicated by a rolling circle mechanism. What is the end result after a round of replication?

• A) a single-stranded DNA that is immediately packaged in the phage head
• B) two molecules resulting from a step of circle-to-circle replication
• C) several circular molecules inserted into each other; the circles are cleaved at the cos sites and eventually relegated
• D) a concatemer (i.e., multiple genomes joined end to tail, which are cleaved at cos sites by a terminase), producing linear double-stranded DNA prior to packaging
• E) several Okazaki fragments that are subsequently ligated

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