A Research Team Is Working on the Design of a New

question 67

Multiple Choice

A research team is working on the design of a new drug for the treatment of lung cancer. To be most effective, this drug must specifically enter the cytoplasm of lung cells while not entering the cells of other tissues. Which of the following characteristics would likely enhance the specificity of this drug?

• A) the relative hydrophobicity of the drug molecule
• B) phospholipid composition of lung cell plasma membranes
• C) specificity of the drug molecule for binding to the extracellular matrix of lung cells
• D) similarity of the drug molecule to other molecules normally transported lung cells

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Definitions:

Angiography

A medical imaging technique used to visualize the inside, or lumen, of blood vessels and organs of the body, with particular interest in the arteries, veins, and the heart chambers.

Aortogram

A radiographic image or angiogram of the aorta obtained after the injection of a contrast medium to visualize the aortic arch and its branching vessels.

Lymphangiogram

A diagnostic imaging test that uses a special dye to visualize the lymphatic system, including lymph nodes and vessels.

Cinematoradiography

A diagnostic technique combining radiography with motion picture techniques to study the movement of internal structures.