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What Are Two Problems Related to Estimating Rates of Disorders

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What are two problems related to estimating rates of disorders in childhood? How might researchers guard against these potential problems?

Appreciate the nuances and complexities of genetic variation, including the effects of migration, mutation rates, and selection pressures.
Understand the principle of Hardy-Weinberg equilibrium and its implications for population genetics.
Comprehend the effects of random mating and gene flow on population genetics.
Analyze evidence for genetic bottlenecks, selection pressures, and the maintenance of genetic diversity.

Definitions:

Monomer

A molecule that can be bonded to other identical molecules to form a polymer.

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