The Folding of Proteins Can Be Considered a Simple Conversion

question 30

Short Answer

The folding of proteins can be considered a simple conversion from the unfolded to the natively folded state. At about 27°C (or 300 K), the free-energy change of folding for a particular protein is measured to be -40 kJ/mole. If the enthalpy change (?H) of folding is -640 kJ/mole, what is the entropy change (?S) of folding for this protein? Write down your answer with the appropriate sign (+ or -) and in kJ/mole/K, e.g. -1000 kJ/mole/K.

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Definitions:

Urinary Bladder

An organ that collects urine excreted by the kidneys before disposal by urination.

Urethra

A tube that conducts urine from the bladder to the outside of the body in both sexes and also conveys semen in males.

Malformations

Abnormalities in the structure of a body part or organ, often present from birth.

Embryo

Developing human from the first to the eighth week of development.