In the First Reaction of the Glycolytic Pathway, the Enzyme

question 12

Multiple Choice

In the first reaction of the glycolytic pathway, the enzyme hexokinase uses ATP to catalyze the phosphorylation of glucose, yielding glucose 6-phosphate and ADP. The ΔG° value for this reaction is -17 kJ/mole. The enzyme glucose 6-phosphatase catalyzes a "reverse" reaction, in which glucose 6-phosphate is converted back to glucose, and a phosphate is released. The ΔG° value for this reaction is -14 kJ/mole. What is the ΔG° value for the following reaction? ATP + H₂O → ADP + Pᵢ

• A) -3 kJ/mole
• B) +3 kJ/mole
• C) -31 kJ/mole
• D) +31 kJ/mole
• E) -15.5 kJ/mole

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