Stable β-Sheet Aggregates Can Form from Many Proteins, Forming Intertwined

question 27

Multiple Choice

Stable β-sheet aggregates can form from many proteins, forming intertwined cross-beta strands that have the potential to kill cells or damage tissues. Which of the following is NOT true regarding these aggregates?

• A) They form almost exclusively in the cells of the nervous system.
• B) Different types of such aggregates can form from the same protein.
• C) Their formation is associated with conditions such as Parkinson's disease and Kuru.
• D) They can form spontaneously, but also can be triggered to form by an infection with the same aggregate.
• E) Some healthy cells form these aggregates to store their secretory proteins.

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