Consider the Two Feed-Forward Loops Below Containing Three Transcription Regulators

question 6

Short Answer

Consider the two feed-forward loops below containing three transcription regulators A, B, and C, where A receives the input signal and C generates the output. In the so-called coherent loop (left), A activates C both directly and indirectly, whereas in an incoherent loop (right), A activates C via one route and inactivates it via the other. Answer the following question(s) based on these network motifs.

-Considering coherent and incoherent feed-forward loops, eight different designs are possible using three components and involving activation (positive) and inhibition (negative) regulation only. In all such loops, A would regulate both B and C, and B would regulate only C. How many of these designs constitute a coherent loop? Write down your answer as a number, e.g. 7.

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Definitions:

Average Variable Costs

The total variable costs of production divided by the quantity of output produced, representing the per-unit variable cost of production.

Drones

Unmanned aerial vehicles (UAVs) that are used for various purposes, including surveillance, delivery, or recreation.

TFC

Total Fixed Costs, referring to the sum of all costs that remain constant regardless of the level of output or production.

TVC

Total Variable Cost, which refers to all costs that vary with the level of output in the production process.