Due to Friction with Molecules of the Surrounding Solution, Sedimenting

question 28

Multiple Choice

Due to friction with molecules of the surrounding solution, sedimenting particles in a mixture reach a terminal velocity when subjected to ultracentrifugation. The sedimentation coefficient (S) for a particle is defined as the ratio of terminal velocity (vt) to the centrifugal acceleration applied to the particle (ac) . S = vt / ac
If each Svedberg unit (S value) is defined as 10-¹³ seconds, approximately how long would it take for a free 50S ribosomal subunit to travel the length of a 9 cm ultracentrifuge tube subjected to a centrifugal force of 50,000 times gravity (g) ? Recall that g is approximately 10 m/s².

• A) 1 min
• B) 10 min
• C) 50 min
• D) 5 h
• E) 10 h

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