Mutations in Two Important Cancer-Critical Genes, Encoding P53 and Rb

question 36

Multiple Choice

Mutations in two important cancer-critical genes, encoding p53 and Rb, respectively, are commonly found in cancers. What type of mutations are these expected to be?

• A) Loss-of-function mutations in both genes
• B) Loss-of-function mutation in p53 and gain-of-function mutation in Rb
• C) Gain-of-function mutation in p53 and loss-of-function mutation in Rb
• D) Gain-of-function mutations in both genes

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