A Single Nucleotide Substitution Within a Gene Is Associated with Type

question 85

Essay

A single nucleotide substitution within a gene is associated with type 1 diabetes and a decrease in insulin secretion. What type of mutation is this? What type of protein (ion channel, hormone, peptide/hormone channel, peptide/hormone pump) is affected?

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Definitions:

Ratification

The act of approving or sanctioning an agreement or treaty that makes it officially valid.

Unauthorized Act

An action taken by an individual or entity without permission or authority, potentially leading to legal consequences or invalidation of the act.

Principal

In finance, this term refers to the original sum of money borrowed in a loan, or the amount of the investment itself, excluding any interest or profit.

Agent

A person or entity authorized to act on behalf of another person or entity in contractual or legal matters.