Succinate Dehydrogenase (SDH) Is an Enzyme Complex Located Within the Inner

question 3

Multiple Choice

Succinate dehydrogenase (SDH) is an enzyme complex located within the inner mitochondrial membrane that catalyzes the oxidation of succinate to fumarate.  An experiment is conducted to determine if malate alters the rate of SDH activity.  Reaction velocity is measured with and without a fixed quantity of malate as succinate concentration is gradually increased.  Obtained results are shown below. Which of the following is the most accurate statement about malate in this experiment?

• A)It alters the maximal velocity of the reaction
• B)It binds the enzyme at a different site than succinate
• C)It covalently binds the enzyme
• D)It decreases affinity of the enzyme for succinate
• E)It is a competitive inhibitor of the enzyme

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Definitions:

Standard Deviation

A statistical measurement that quantifies the dispersion or spread of a set of data points around the mean.

Raw Scores

A raw score is the initial, unadjusted score obtained directly from the number of questions answered correctly on a test or assessment.

Test-retest Reliability

The consistency of test scores obtained by the same individuals over successive administrations of the same test.

Percentile

A statistical measure indicating the value below which a given percentage of observations in a group of observations fall.