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Geneticists Are Studying a Malfunctioning Protein That Causes Impaired Endothelial

question 11

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Geneticists are studying a malfunctioning protein that causes impaired endothelial cell migration and angiogenesis.  They have noticed that the amino acid sequence of the protein is truncated compared to normal controls.  The mutated mRNA strand is isolated, and analysis shows a nonsense mutation located near the 3' end of the coding region.  The 3' terminal coding sequence of the abnormal mRNA strand is shown below. Geneticists are studying a malfunctioning protein that causes impaired endothelial cell migration and angiogenesis.  They have noticed that the amino acid sequence of the protein is truncated compared to normal controls.  The mutated mRNA strand is isolated, and analysis shows a nonsense mutation located near the 3' end of the coding region.  The 3' terminal coding sequence of the abnormal mRNA strand is shown below.   Which of the following tRNA anticodons is responsible for adding the last amino acid to the truncated polypeptide during protein translation? A) 5'-AAC-3' B) 5'-AUC-3' C) 5'-CAA-3' D) 5'-GCU-3' E) 5'-UCG-3' Which of the following tRNA anticodons is responsible for adding the last amino acid to the truncated polypeptide during protein translation?


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