A Clinical Study Examines the Usefulness of 5 Different Biomarkers

question 101

Multiple Choice

A clinical study examines the usefulness of 5 different biomarkers to detect Barrett esophagus (BE) , the only known precursor lesion of esophageal adenocarcinoma.  Researchers evaluate the performance of each biomarker and report the sensitivity, specificity, and area under the curve (AUC) estimates. Which of the biomarkers is most accurate?

• A)1
• B)2
• C)3
• D)4

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Definitions:

Genus

A rank in the biological classification system (taxonomy) that is used to group species sharing common characteristics, directly above species and below family.

Species

A fundamental classification in biology, denoting groups of organisms that can reproduce fertile offspring, sharing common characteristics and genetic similarity.

Homology

in biology, refers to traits or organs that have a common ancestry despite potentially having different functions, while in cultural studies it can refer to similarities in patterns or structures based on shared heritage.

Subspecies

A subdivision within a species, characterized by distinct genetic, morphological, or behavioral traits, often resulting from geographical isolation.