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A 23-Year-Old Man Is Being Evaluated for Myoclonic Epilepsy of Recent

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A 23-year-old man is being evaluated for myoclonic epilepsy of recent onset.  The episodes are short-lived and triggered by startle.  Physical examination reveals proximal muscle weakness.  Gomori trichrome stain of a muscle biopsy specimen shows muscle fibers with a blotchy red appearance.  No family history is available because the patient is adopted.  What is the probability that this patient's one offspring will inherit the disease?

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Definitions:

Pension Liability

The amount of money a company is required to pay into its employees' retirement plans in the future.

Accumulated Benefit Obligation

An estimate of the total amount of an employer's obligation for pension benefits earned by employees to date, not based on future salary increases.

Plan Assets

Assets specifically identified to fund the obligations of a pension or other employee benefit plan.

Pension Funding

The financial contributions made by a company to a defined benefit pension plan to meet future pension obligations to retirees.

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