Researchers Are Studying Various Cellular Processes in Normal and Diseased

question 126

Multiple Choice

Researchers are studying various cellular processes in normal and diseased states to find new anticancer drug targets.  They develop a medication that inhibits an intracellular enzyme that converts adenosine to inosine.  With drug use, accumulation of enzyme substrates in the neoplastic cells leads to DNA strand breaks and subsequent apoptosis.  Which of the following malignancies is likely to be most responsive to this medication?

• A)Hairy cell leukemia
• B)Malignant melanoma
• C)Ovarian teratoma
• D)Small cell lung cancer
• E)Soft tissue sarcoma

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Definitions:

Scalar Chain Principle

A concept in organizational theory that suggests a clear line of authority from the top management to the lowest ranks.

Hierarchical Structure

An organizational structure where entities are ranked one above the other according to authority or status.

Managerial Overrides

When a manager or leader bypasses existing procedures, policies, or systems, often to make a decision or take direct action.

Bureaucracy

A system of government or management involving multiple layers of administration, strict policies, and rigid adherence to rules.