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A 44-Year-Old Man with Diabetic Nephropathy Undergoes a Renal Transplant

question 84

Multiple Choice

A 44-year-old man with diabetic nephropathy undergoes a renal transplant. One week later, he develops low-grade fever, body aches, and decreased urine output. Temperature is 37.2 C (99 F) , blood pressure is 124/76 mm Hg, and pulse is 88/min. Physical examination shows mild tenderness over the graft on palpation. Serum creatinine is 2.2 mg/dL, an increase from 1.2 mg/dL two days ago. Arterial and venous Doppler studies reveal adequate graft perfusion. Graft biopsy demonstrates dense interstitial infiltration by mononuclear cells. Which of the following is the most likely cause of this patient's current condition?

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Definitions:

Prohibition

The legal act of prohibiting the manufacture, storage, transportation, and sale of alcohol which was in effect in the United States from 1920 to 1933.

Lax Enforcement

Lax enforcement refers to a situation where rules, laws, or regulations are not strictly applied or are inadequately followed by authorities.

Organized Crime

A category of transnational, national, or local groupings of highly centralized enterprises run by criminals who intend to engage in illegal activity, most commonly for profit.

Jazz

A music genre originating in the African-American communities of New Orleans, USA, in the late 19th and early 20th centuries, known for its distinctive rhythm, improvisation, and use of brass and woodwind instruments.