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A 24-Year-Old Man Comes to the Emergency Department Due to Bloody

question 185

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A 24-year-old man comes to the emergency department due to bloody diarrhea.  His symptoms began 10 days ago with episodic abdominal discomfort and loose stools.  The symptoms have progressively worsened, and he has had 6-8 stools mixed with blood and mucus over the past 2 days.  The patient recently returned from a 2-week trip to Egypt and felt well while traveling.  Temperature is 38 C (100.4 F) , blood pressure is 120/70 mm Hg, and pulse is 86/min.  The abdomen is soft with mild tenderness on palpation of lower quadrants.  There is no guarding or rebound tenderness, and bowel sounds are hyperactive.  Stool testing is negative for C difficile toxin, and stool culture yields no bacteria.  Sigmoidoscopy reveals colonic ulcers with undermining edges that contain trophozoites.  The causative organism for this patient's current condition can also produce which of the following manifestations?


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