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A 50-Year-Old Man Comes to the Office for Evaluation of Abdominal

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A 50-year-old man comes to the office for evaluation of abdominal fullness and mild right flank pain.  He also reports a weight loss of 4.5 kg (10 lb) over the past 2 months.  The patient has no other medical issues and works in a local industrial chemical manufacturing facility.  Examination shows a soft abdomen.  Ultrasound reveals a mass in the right kidney.  A subsequent abdominal CT scan confirms the presence of a large right renal mass with evidence of necrosis.  The patient undergoes a right total nephrectomy.  The specimen is shown below. A 50-year-old man comes to the office for evaluation of abdominal fullness and mild right flank pain.  He also reports a weight loss of 4.5 kg (10 lb)  over the past 2 months.  The patient has no other medical issues and works in a local industrial chemical manufacturing facility.  Examination shows a soft abdomen.  Ultrasound reveals a mass in the right kidney.  A subsequent abdominal CT scan confirms the presence of a large right renal mass with evidence of necrosis.  The patient undergoes a right total nephrectomy.  The specimen is shown below.   This patient's lesion most likely originated from which of the following portions of the kidney? A) Blood vessels B) Collecting duct cells C) Glomeruli D) Proximal renal tubules E) Renal pelvis lining This patient's lesion most likely originated from which of the following portions of the kidney?

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