A 72-Year-Old Man Is Hospitalized Due to Fatigue, Orthopnea, and Exertional

question 290

Multiple Choice

A 72-year-old man is hospitalized due to fatigue, orthopnea, and exertional dyspnea.  The patient takes no medications and has not seen a physician in many years.  He is a lifelong nonsmoker.  His blood pressure is 110/60 mm Hg and pulse is 64/min.  Examination reveals bibasilar crackles, elevated jugular venous pressure, and bilateral lower extremity pitting edema.  His left ventricular end-diastolic pressure-volume is shown in the graph below (purple curve) . Which of the following is the most likely cause of this patient's condition?

• A)Alcohol-induced cardiomyopathy
• B)High-dose doxorubicin therapy
• C)Selenium deficiency
• D)Transthyretin deposition
• E)Viral myocarditis

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Definitions:

Eudicots

A classification of flowering plants (angiosperms) that are characterized by having two seed leaves (cotyledons).

Venation

The pattern of veins in the leaves, stems, and petals of plants, critical for transport and support.

Reproductive Success

A measure of an individual's genetic contribution to the next generation, often assessed by the number of surviving offspring produced.

Flowering Plants

Plants belonging to the group Angiosperms, characterized by producing flowers in which their seeds develop.