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A 64-year-old man comes to the office due to urinary frequency, hesitancy, and dribbling. His symptoms began insidiously 5 years ago and have progressively worsened. He has to get up 2 or 3 times each night to urinate. Vital signs are normal. Examination shows a smooth, symmetrically enlarged prostate without nodules or tenderness. There is no suprapubic tenderness. Prostate-specific antigen level is 3.5 ng/mL, creatinine is 1.2 mg/dL, and urinalysis is normal. The patient is started on a new medication. After 6 months of therapy, his urinary symptoms improve and prostate volume decreases by 20%. Which of the following medications is most likely responsible for the decreased prostate volume in this patient?
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