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A 35-Year-Old Man with a Known History of Peptic Ulcer

question 221

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A 35-year-old man with a known history of peptic ulcer disease comes to the physician with sudden onset of pain, swelling, and redness at the base of his great toe.  The patient was awakened in the middle of the night by the pain and was unable to go back to sleep.  He has no history of trauma to the joint.  Physical examination shows swelling, erythema, and exquisite tenderness involving the right first metatarsophalangeal joint.  Fine-needle aspiration of the joint shows needle-shaped, negatively birefringent crystals.  After making the diagnosis, the physician prescribes an appropriate medication.  Shortly after starting the medication, the patient develops nausea, vomiting, and diarrhea.  Which of the following is the most likely mechanism of action of the drug prescribed to this patient?


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Four Dichotomies

Refers to the four pairs of opposite preferences in the Myers-Briggs Type Indicator (MBTI), used to categorize personality types.

Myers-Briggs Type Indicator

A psychological assessment tool that categorizes individuals into personality types based on their preferences in perceiving the world and making decisions.

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