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A 41-Year-Old Man Comes to the Emergency Department Due to 3

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A 41-year-old man comes to the emergency department due to 3 weeks of low-grade fever, productive cough, and a 4.5-kg (10-lb) weight loss.  The patient drinks 10-12 beers a day.  On physical examination, he appears cachectic.  Poor dentition and clubbing of the fingers are noted.  A foul-smelling sputum sample is expectorated and sent for Gram stain and culture.  CT scan of the chest is shown in the image below: A 41-year-old man comes to the emergency department due to 3 weeks of low-grade fever, productive cough, and a 4.5-kg (10-lb)  weight loss.  The patient drinks 10-12 beers a day.  On physical examination, he appears cachectic.  Poor dentition and clubbing of the fingers are noted.  A foul-smelling sputum sample is expectorated and sent for Gram stain and culture.  CT scan of the chest is shown in the image below:   Empiric antimicrobial therapy should include coverage against which of the following pathogens? A) Cell wall-deficient bacteria B) Intestinal gram-negative flora C) Resident skin microbiota D) Staphylococci resistant to beta-lactams E) Strict and facultative anaerobes Empiric antimicrobial therapy should include coverage against which of the following pathogens?


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