An 80-Year-Old Man Participates in a Study Designed to Evaluate

question 181

Multiple Choice

An 80-year-old man participates in a study designed to evaluate the effects of aging on the liver.  He has undergone a liver biopsy every 10 years since age 40 so that researchers can identify age-related histologic changes.  The subject is healthy and has no relevant family history.  He does not use alcohol or illicit drugs.  BMI is 21.5 kg/m².  Physical examination is unremarkable; laboratory studies, including complete blood count, liver function tests, cholesterol levels, and hemoglobin A1c, are within normal limits.  Which of the following histologic changes has most likely developed over time in this individual?

• A)Extracellular amyloid deposition
• B)Hemosiderin collections within hepatocytes
• C)Hepatocyte intracytoplasmic hyaline inclusions
• D)Lipofuscin deposition within hepatocytes
• E)Stellate cell collagen production

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Definitions:

TV

A widely used electronic device that receives sound and visual images, transmitting them to viewers and serving both entertainment and educational purposes.

Models of Abnormality

Theories and frameworks used to understand the causes, symptoms, and treatments of psychological disorders, including biological, psychological, and sociocultural models.

Laboratory Testing

The analysis of blood, urine, or other body fluids or tissues in a controlled environment to diagnose, prevent, or treat diseases.

Psychodynamic

An approach in psychology that emphasizes systematic study of the psychological forces that underlie human behavior, feelings, and emotions and how they might relate to early experiences.