An 80-Year-Old Man Participates in a Study Designed to Evaluate

question 181

Multiple Choice

An 80-year-old man participates in a study designed to evaluate the effects of aging on the liver.  He has undergone a liver biopsy every 10 years since age 40 so that researchers can identify age-related histologic changes.  The subject is healthy and has no relevant family history.  He does not use alcohol or illicit drugs.  BMI is 21.5 kg/m².  Physical examination is unremarkable; laboratory studies, including complete blood count, liver function tests, cholesterol levels, and hemoglobin A1c, are within normal limits.  Which of the following histologic changes has most likely developed over time in this individual?

• A)Extracellular amyloid deposition
• B)Hemosiderin collections within hepatocytes
• C)Hepatocyte intracytoplasmic hyaline inclusions
• D)Lipofuscin deposition within hepatocytes
• E)Stellate cell collagen production

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Definitions:

Comparative Advantage

The ability of an individual or group to produce a good or service at a lower opportunity cost than others, leading to more efficient trade possibilities.

Production Possibility

A graph showing the highest possible production levels of two items, using a specific combination of resources and various factors.

Opportunity Costs

Making a choice results in the loss of potential profit that could have been earned from choosing differently.

Increasing Opportunity

In economic terms, refers to the increasing cost associated with producing additional units of a good, implying that producing more of one good requires sacrificing increasingly larger amounts of another good.