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An Analysis of Results from 18,317 Patients Pooled from 5

question 426

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An analysis of results from 18,317 patients pooled from 5 large randomized controlled trials on drug X revealed the following relative rates (RR) for drug X compared to the control:
RR of cardiovascular mortality = 0.90 (95% confidence interval [CI], 0.73-1.38)
RR of heart failure = 2.09 (95% CI, 1.52-2.88)
RR of myocardial infarction = 1.18 (95% CI, 0.86-1.31)
Based on the results of this meta-analysis, there is a statistically significant increase in which of the following events among patients taking drug X?


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