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A 40-Year-Old Man Seeks Evaluation for Edema

question 77

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A 40-year-old man seeks evaluation for edema.  Two days ago, he had sudden onset of swelling in his legs.  There was no associated warmth, redness, or tenderness.  The patient had a mild cold a week ago and was taking over-the-counter cold remedies.  He thought the swelling was an allergic reaction that would go away, but it has not.  His past medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  He takes no prescription or over-the-counter medications.  There is no family history of kidney disease.
The patient's temperature is 36.7 C (98.1 F) , blood pressure is 120/70 mm Hg, and pulse is 78/min.  He has 3+ pitting edema to the mid-thigh bilaterally.  Otherwise, his physical examination is unremarkable.
Laboratory results are as follows:
A 40-year-old man seeks evaluation for edema.  Two days ago, he had sudden onset of swelling in his legs.  There was no associated warmth, redness, or tenderness.  The patient had a mild cold a week ago and was taking over-the-counter cold remedies.  He thought the swelling was an allergic reaction that would go away, but it has not.  His past medical history is unremarkable.  The patient does not use tobacco, alcohol, or illicit drugs.  He takes no prescription or over-the-counter medications.  There is no family history of kidney disease. The patient's temperature is 36.7 C (98.1 F) , blood pressure is 120/70 mm Hg, and pulse is 78/min.  He has 3+ pitting edema to the mid-thigh bilaterally.  Otherwise, his physical examination is unremarkable. Laboratory results are as follows:   Which of the following diagnoses is most likely to be made with renal biopsy? A) Allergic interstitial nephritis B) IgA nephropathy C) Membranoproliferative glomerulonephritis D) Minimal change disease E) Postinfectious glomerulonephritis
Which of the following diagnoses is most likely to be made with renal biopsy?


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