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A 33-Year-Old Man with a History of Multiple Sclerosis Is

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A 33-year-old man with a history of multiple sclerosis is brought to the emergency department due to new-onset leg weakness, numbness, and urinary incontinence.  In the past, he has had several acute exacerbations of multiple sclerosis, causing vertigo, vision impairment, and upper extremity weakness, all of which improved after glucocorticoid treatments.  A year ago he stopped taking disease-modifying therapy due to severe adverse effects.  His vital signs are within normal limits.  Mental status and cranial nerve examination are normal.  Muscle strength in the upper extremities is 5/5 and in the lower extremities is 3/5.  Pinprick sensation is decreased below the nipple.  Proprioception is decreased over both lower extremities.  Babinski reflex is present bilaterally.  MRI of this patient is most likely to reveal new plaques in which of the following locations?


Definitions:

Direct Materials Purchases Variance

The difference between the actual cost of direct materials purchased and the expected (budgeted) cost of these materials.

Standard Direct Labor-Hours

The estimated amount of labor time required to produce one unit of output, based on established standards.

Variable Overhead Rate Variance

The difference between the actual and the standard cost of variable overheads in a production process.

Direct Materials Purchases Variance

The difference between the actual cost of direct materials purchased and the expected (or standard) cost, used for budgeting and cost control purposes.

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