Lynch Syndrome Occurs as a Result of Defect in One

question 1

Multiple Choice

Lynch syndrome occurs as a result of defect in one or several genes that are important in detection and repair of DNA base-pair mismatches. What is the phenotypic abnormality that results as a mutation in an allele of a mismatch repair (MMR) gene?

• A) Chromosomal instability
• B) Nucleotide instability
• C) Macrosatellite instability
• D) Microsatellite instability

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Definitions:

Parasympathetic

Part of the autonomic nervous system responsible for conserving energy and facilitating rest and digestion processes.

Somatic

Relating to the body, especially as distinct from the mind or psyche.

Central

Pertaining to the primary or most important part of something, often the center or core.

Depolarized

A state in which the difference in electric charge across the cell membrane is reduced, affecting cell function.