Why Would Interference with Topoisomerase II Cause Clastogenesis

question 4

Essay

Why would interference with topoisomerase II cause clastogenesis?

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Definitions:

Cardiac Cycle

The sequence of events in the heart from one heartbeat to the next, including systole and diastole.

Systolic Cycle

The phase of the heartbeat when the heart muscle contracts and pumps blood from the chambers into the arteries, raising arterial blood pressure.

Diastolic Cycle

The phase of the heart cycle during which the heart muscles relax and the chambers of the heart fill with blood.

Korotkoff Phase

Sounds heard over an artery when blood pressure is measured, used to identify systolic and diastolic pressures.