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Jason E. Klein and Alan R. Fleischman | The Private Practicing Physician-Investigator: Ethical Implications of Clinical Research in the Office Setting
Klein and Fleischman discuss the conflicts of interest in contemporary medical research due to the shift in recent decades from clinical trials based in academic centers to pharmaceutical company-based recruitment of "patient-subjects" directly through private practicing "physician-investigators." They conclude with a number of recommendations to reduce or eliminate these conflicts.
-With the shift of clinical research outside of academic centers, thousands of private physicians have become ___________ while their patients have become patient-subjects.
Basale
Refers to the deepest layer of the epidermis or other epithelial tissues.
Sensory Corpuscles
Specialized nerve endings found in the skin that respond to light touch and pressure.
Melanocytes
Cells located in the bottom layer of the skin's epidermis that produce melanin, the pigment responsible for skin color.
Avascular
Characterized by or pertaining to tissues that do not contain blood vessels; often referring to areas where healing may be impaired due to lack of blood flow.
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