A Key Event That Triggers Puberty Is an Increase in GnRH

question 124

Multiple Choice

A key event that triggers puberty is an increase in GnRH secretion by the hypothalamus, which subsequently activates gonadotropin secretion. Precocious (early-onset) puberty is often treated by manipulating this hormonal system with

• A) pulsatile administration of LH and FSH analogs.
• B) pulsatile administration of GnRH analogs.
• C) administration of LH and FSH analogs at constant high levels.
• D) administration of GnRH analogs at constant high levels.
• E) administration of high doses of estrogen to reduce GnRH levels through feedback inhibition.

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