How Does the Presence of High Concentrations of Extracellular Magnesium

question 46

Multiple Choice

How does the presence of high concentrations of extracellular magnesium or cadmium ions block transmitter release?

• A) Magnesium and cadmium compete with calcium for passage through the presynaptic voltage-gated calcium channel, preventing calcium entry.
• B) Magnesium and cadmium compete with sodium for passage through the presynaptic voltage-gated sodium channel.
• C) Magnesium and cadmium directly block synaptic vesicle fusion with the plasma membrane.
• D) Magnesium and cadmium block presynaptic action potentials.
• E) Magnesium and cadmium compete with potassium for passage through the presynaptic voltage-gated potassium channel.

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