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When Using the Cell-Attached Patch Clamp Recording Technique to Record

question 46

Essay

When using the cell-attached patch clamp recording technique to record single potassium channel currents from cardiac muscle cells, explain why muscarinic receptor agonists applied to the bath outside of the patch are unable to activate these potassium channels?


Definitions:

Molecular Polarity

A characteristic of a molecule with uneven distribution of electron density, resulting in the molecule having a positive end and a negative end.

Carbon Monoxide

A colorless, odorless, and tasteless gas produced by incomplete combustion, toxic to humans and animals when inhaled.

Molecular Polarity

A characteristic of molecules where there is an unequal distribution of electrons between atoms, leading to a molecule having a positive end and a negative end.

Methane Molecule

A chemical compound with the formula CH4, the simplest alkane and the main component of natural gas, consisting of one carbon atom surrounded by four hydrogen atoms.

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