What Is Currently the BEST Explanation for What Determines Whether

question 1

Multiple Choice

What is currently the BEST explanation for what determines whether a T cell develops into a CD8⁺ T cell or a CD4⁺ T cell?

• A)CD4/TCR coengagement suppresses CD8 expression, and CD8/TCR coengagement suppresses CD4 expression.
• B)T cells randomly downregulate CD4 or CD8, and only cells that still bind the appropriate MHC will get a strong enough signal to survive.
• C)CD4 or CD8 expression is determined by the strength and duration of the TCR/MHC interaction.
• D)CD4 or CD8 expression is predestined in the bone marrow.
• E)Only ?? T cells express CD8.

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Definitions:

Pros

The advantages or positive aspects of a situation or decision.

Cons

The arguments, reasons, or factors opposing an idea, decision, or action; the drawbacks or disadvantages.

Gains

Benefits or profits accrued from investments, efforts, or other activities.

Losses

The state of being deprived of or of being without something that one has had or the detrimental impact resulting from such a situation.