Which of the Following BEST Encapsulates the Findings of the Hozumi

question 9

Multiple Choice

Which of the following BEST encapsulates the findings of the Hozumi and Tonegawa experiments?

• A)Every possible light chain that could be formed, in terms of receptor specificity, is encoded by a separate gene within the human genome.
• B)Light chains are produced by means of somatic rearrangement of germ-line DNA in B cells.
• C)The different light-chain variable regions are produced by means of alternative splicing of pre-mRNA that has been transcribed from a fixed, unchanging DNA sequence.
• D)Different light chains, each with unique specificity, are produced via the activity of alternative transcription factors that regulate antibody production at the level of transcription initiation.
• E)None of the answers are correct.