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When Two Heterozygotes Are Mated, the Ratios of the Offspring

question 48

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When two heterozygotes are mated, the ratios of the offspring produced should be in a 1:2:1 ratio if normal Mendelian segregation is occurring. If one of the alleles is dominant, then the phenotypes observed should be present in a 3:1 ratio with the dominant phenotype more common than the recessive one. We can use a χ2 goodness-of-fit test to test whether the ratio of offspring is indeed 3:1. Imagine a cross is performed and the number of offspring observed are 67 with the dominant phenotype and 33 with the recessive phenotype. What is the χ2 value we would obtain?


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