The PKD1 Gene Encoding Polycystin-1 Is a Large Integral Membrane

question 5

Multiple Choice

The PKD1 gene encoding polycystin-1 is a large integral membrane protein. It is typically found in persons who have which of the following diseases?

• A) Childhood polycystic kidney disease
• B) Adult polycystic disease
• C) Adult onset renal medullary cystic disease
• D) Glomerulocystic disease
• E) Acquired renal cystic disease

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Definitions:

Co-efficient Of Relatedness

A measure of the genetic similarity between two individuals, often used to predict the likelihood of gene sharing.

Hamilton's Rule

A principle in evolutionary biology stating that an individual will act to increase its own genetic success, potentially aiding related individuals at a cost to itself if the genetic benefits exceed the costs.

Intersexual Selection

A mode of natural selection where members of one biological sex choose mates of the other sex to mate with, often based on certain desirable characteristics.

Polyandry

A mating system in which a female mates with several males during a breeding season. Compare with polygyny.