Trinucleotide CTG Repeat Expansion Plays a Role in the Pathogenesis

question 5

Multiple Choice

Trinucleotide CTG repeat expansion plays a role in the pathogenesis of which of the following muscle diseases?

• A) Duchenne muscular dystrophy
• B) Becker muscular dystrophy
• C) Autosomal dominant limb girdle muscular dystrophy
• D) Autosomal recessive limb girdle muscular dystrophy
• E) Myotonic dystrophy

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Definitions:

Brain Damage

The destruction or degeneration of brain cells due to injuries, diseases, or conditions, affecting cognitive, physical, and emotional functions.

Magnetic Resonance Spectroscopy

A non-invasive analytical technique that uses magnetic fields to identify and quantify molecular compounds within tissues.

N-acetylaspartate (NAA)

A compound found in neurons, considered a marker for neuronal health and integrity often used in brain spectroscopy studies.

Contrecoup Injury

A contrecoup injury is a type of brain injury that occurs on the side opposite the impact, caused by the brain striking the skull following a forceful blow or shock to the head.