All of the Following Are Early T Cell Events That

question 9

Multiple Choice

All of the following are early T cell events that occur after antigen recognition by the TCR EXCEPT:

• A)Formation of the immunologic synapse
• B)Recruitment of signaling molecules,such as LAT,to glycolipid-enriched domains known as lipid rafts
• C)Enhanced adhesion between T cells and antigen-presenting cells (APCs)via T cell integrin LFA-1 and its ligand on the APC,ICAM-1,at the central zone of the immunologic synapse
• D)Clustering of the TCR and coreceptors leading to phosphorylation of ITAMs on CD3 by Lck
• E)Binding of CD28 with costimulators on APCs in the cSMAC,resulting in signal transduction activation

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Definitions:

ABC Transporter

A large family of proteins that transport various molecules across extracellular and intracellular membranes, using energy from ATP hydrolysis.

Cotransport

A mechanism where two substances are simultaneously transported across a membrane by a single protein, a process that is typically energy-efficient.

Exocytosis

A process by which a cell transports secretory products through the cytoplasm to the plasma membrane and then releases them into the extracellular environment.

Lysis

The process of disintegration of a cell or some other structure.