A 47-Year-Old Woman Had a Mastectomy Because She Had Breast

question 9

Multiple Choice

A 47-year-old woman had a mastectomy because she had breast carcinoma that was previously diagnosed by biopsy.Pathologic examination revealed that several axillary lymph nodes contained metastatic tumors.A test was performed on tumor cells extracted from the mastectomy specimen,which indicated that the tumor cells overexpressed a certain cellular proto-oncogene.On the basis of this test result,the patient was treated with an FDA-approved monoclonal antibody specific for the protein encoded by that gene.Which of the following was most likely the protein target of this antibody therapy?

• A)p53
• B)H-Ras
• C)HPV E7
• D)Rb
• E)Her2

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Definitions:

Net Operating Income

A measure of a company's profitability from its regular business operations, excluding taxes and interest.

Interest Rate

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Debt Ratio

A financial ratio that measures the extent of a company’s leverage, specifically the ratio of its total liabilities to its total assets.

Business Risk

The exposure to uncertainty and potential loss in a company’s operations due to factors like fluctuations in revenue or expenses.