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The Novel Basic Drug Methcathinone Has a PKa of 8

question 5

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The novel basic drug methcathinone has a pKa of 8. OF is collected from a driver stopped for possible DUI and is tested in a forensic toxicology laboratory. Assuming the blood is at physiological pH and the OF has a pH of 6.5, the concentration detected in the OF is likely to be _________ than the plasma concentration.


Definitions:

Cocaine

An illicit narcotic with central nervous system stimulant effects, widely abused for its euphoric effects and potential for addiction.

Caffeine

A stimulant commonly found in coffee, tea, and other beverages, known for enhancing alertness and temporarily warding off drowsiness.

Caffeine

A stimulant found in coffee, tea, and various sodas and energy drinks, known for its ability to temporarily ward off drowsiness and restore alertness.

Stimulant

A substance that raises levels of physiological or nervous activity in the body, often used therapeutically to increase alertness or physical performance.

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