Which of the Following Statements Is True Regarding Posttranslational Modification

question 3

Multiple Choice

Which of the following statements is true regarding posttranslational modification of alkaline phosphatase (ALP) isoenzymes?

• A)ALP isoforms result from the cleavage of terminal amino acids, creating variations in electrical charge and allowing separation by electrophoresis.
• B)ALP isoforms result from the addition of carbohydrate side chains, which do not significantly modify electrical charge, making separation by electrophoresis difficult.
• C)ALP isoforms result from dephosphorylation reactions that significantly alter the charge of the isoforms, allowing separation by electrophoresis.
• D)ALP isoforms result from the addition of lipoprotein side chains, which do not significantly modify electrical charge, making separation by electrophoresis difficult.

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